Литература к главе 9 и приложению 8

2253. Adinolfi A., Adinolfi M., Lessof M. H. (1975). Review: Alphafetoprotein during development and in disease, J. Med. Genet., 12, 138-151.

2254. Anonymous (1977). Methods for the detection of haemophilia carriers: a memorandum, WHO Bull., 55, 675-702.

2255. Anonymous (1975). Law and ethics of A. I. D. and embryo transfer, Ciba Found Symp. (new series), 17.

2256. Anonymous (1975). National Research Council. Committee for the Study of Inborn Errors of Metabolism. Genetic screening: programs, principles, and research, National Academy of Sciences, Washington (D. C.).

2257. Anonymous (1985). Embryo research, Lancet, 1, 255-256.

2258. Anonymous (1983). President's Commission for the Study of Ethical Problems in Medicine and Biomedical Research: Screening and Counseling for Genetic Conditions, The Ethical, Social, and Legal Implications of Genetic Screening, Counseling, and Education Program, US Government Printing Office, Washington, DC.

2259. Anonymous (1984). Report of the Committee on Inquiry into Human Fertilisation and Embryology, Her. Majesty's Stationery Office, London.

2260. Anonymous (1985). Maternal serum alpha-fetoprotein screening for neural tube defects. Results of a consensus meeting, Pren. DiaG., 5, 77-83.

2261. Anonymous (1985). Low maternal serum alphafetoprotein and Down syndrome, Lancet, 1, 259-260.

2262. Applebaum E. G., Firestein S. K. (1983). A Genetic Conseling Casebook, The Free Press, New York.

2263. Bakker E., Hqfker M. H., Goor N., Mandel J. L., Wrogemann K., Davies K. E., Kunkel L. M., Willard H. F., Fenton W. A., Sandkuyl L., Majoor-Krakauer D., Essen A. J. V., Jahoda M. G. J., Sachs E.S., van Ommen G. J. B., Pearson P. L. (1985). Prenatal diagnosis and carrier detection of Duchenne muscular dystrophy with closely linked RFLPs, Lancet, 1, 655-658.

2264. Berg P., Baltimore D., Boyer H. W., Cohen S. N., Davis R. W., Hogness D. S., Nathans D., Roblin R. O., Watson J. D., Weissman S., Zinder N.D. (1974). Potential biohazards of recombinant DNA molecules, Science, 185, 303.

2265. Bloch E. V., DiSalvo M., Hall B. D., Epstein C. J. (1979). Alternative ways of presenting empiric risks. In: Risk, Communication, and Decision Making in Genetic Counseling, Epstein С. J., Curry C. J. R., Packman S., Sherman S., Hall B. D. (eds.), Birth Defects, OriG. Art Ser. XV/5C., Alan. R. Liss, New York.

2266. Bonaiti-Pellie C., Phung L., Nordmann Y. (1984). Recurrence risk estimation of acute intermittent porphyria based on analysis of porphobilinogen deaminase activity: A Bayesian approach, Am. J. Med. Genet., 19, 755-762.

2267. Brambati В., Simoni G., Danesino C., Oldrini A., Ferrazzi E., Romitti L., Terzoli G., Rossella F., Ferrari M., Fraccaro M. (1985). First trimester fetal diagnosis of genetic disorders: clinical evaluation of 250 cases, J. Med. Genet, 22, 92-99.

2268. Campbell S., Pearce J. M. (1983). Ultrasound visualization of structural anomalies, Br. Med. Bull., 39, 322.

2269. Cao A., Cossu P., Falchi A. M., Monni G., Pirastu M., Rosatelli C., Scalas M. Т., Tuveri T. (1985). Antenatal diagnosis of thalassemia major in Sardinia, Ann. N. Y. Acad. Sci., 445, 380-302.

2270. Capron A. M., Lappe M., Murray R. F., Powledge T. M., Twiss S. В., Bergsma D. (eds.) (1979). Genetic counselling: facts, values, and norms, Birth Defects, OriG. Art Ser. XV(2), Alan R. Liss, New York.

2271. Carter C. O., Fraser Roberts J. A., Evans K. A., Buck A.R. (1971). Genetic clinic: a fallowup, Lancet, 1, 281.

2272. Char gaff E. (1976). On the dangers of genetic meddling, Science, 192, 938.

2273. Cote G. B. (1982). Odds in genetic counseling, J. Med. Genet, 19, 455-457.

2274. Crandall B. F., Robertson R. D., Lebherz T. B., King W., Schroth P. С (1983). Maternal serum a-fetoprotein screening for the detection of neural tube defects, West J. Med., 138, 531-534.

2275. Cuckle H. S., Wald N. J., Lindenbaum R. H. (1984). Maternal serum alpha-fetoprotein measurement: a screening test for Down syndrome, Lancet, 1, 926-929.

2276. Dalgaard O. Z. (1957). Bilateral polycystic disease of the kidneys. A follow-up two-hundred and eightyfour patients and their families, Acta Med. Scand., 328 [suppl.].

2277. Davis B. D. (1977). The recombinant DNA scenarios: Andromeda strain, chimera, and golem, Sci. Am., 65, 547-555.

2278. Di Lonardo A. M., Orrego C., Darlu P., King M.-C., Baw М. (1984). Human genetics and human rights. Identifying the families of kidnapped children, Am. J. Foren. Med. Pathol, 5, 339-347.

2279. Din N., Schwartz M., Kruse Т., Vestergaard S. R., Ahrens P., Caput D., Hartog K., Quiroga M. (1985). Factor VIII gene specific probe for prenatal diagnosis of haemophilia A, Lancet 1 1446-1447.

2280. Dworkin R. В., Omenn G. S. (1985). Legal aspects of human genetics, Ann. Rev. Public. Health., 6, 107-130.

2281. Edwards R. G., Fowler R.E. (1970). The genetics of preimplantation human development, Mod. Trends. Hum. Genet., Vol. 1, 181-213.

2282. Edwards R. G., Steptoe P. С (1973). Biological aspects of embryo transfer, pp. 11-18, Law and ethics of A. I. D. and embryo transfer, Ciba Found. Symp. (new series), 17, 11-18.

2283. Elles R. G., Williamson R., Niazi M., Coleman D. V., Horwell D. (1983). Absence of maternal contamination of chorionic villi used for fetal gene analysis, N. Engl. J. Med., 308, 1433.

2284. Emery A. E. H., Pullen I. (1984). Psychologic aspects of genetic counseling, Academic Press.

2285. Epstein C. J. (1975). Genetic counseling: present status and future prospects. In: Early diagnosis and prevention of genetic disease, Went L., Vermeji-Keers C., Linden A. G. J. M. van der (eds.), University of Leiden Press, Leiden, pp. 110-131.

2286. Epstein C. J., Cox D. R., Schonberg S. A., Hogge W.A. (1983). Recent developments in the prenatal diagnosis of genetic diseases and birth defects, Ann. Rev. Genet., 17, 49-83.

2287. Epstein С. J., Curry С. J. R., Packman S., Sherman S., Hall B.D. (1979). Risk, Communication, and Decision Making in Genetic Counseling, Birth Defects, OriG. Art Ser. XV(5C), Alan R. Liss, New York.

2288. Erbe R. W. (1975). Screening for the hemoglobinopathies. In: The prevention of genetic disease and mental retardation, Milunsky A. (ed.), Saunders, Philadelphia, pp. 204-220.

2289. Evers-Kiebooms G., Berghe H. van den (1979). Impact of genetic counseling: a review of published followup studies, Clin. Genet., 15, 465-474.

2290. Falk R., Motulsky A. G., Vogel F., Weingart P. (1985). Historische und ethische Aspekte der Humangenetik. Ein Interdisziplinares Kolloquiuim Wissenschaftskolleg, in Wissenschaftskolleg - Institute for Advanced Study - Berlin Yearbook 1983/84, Siedler Verlag, Berlin, pp. 75-121.

2291. Farrow M. G., Juberg R. C. (1969). Genetics and laws prohibiting marriage in the United States, JAMA, 209, 534.

2292. Ferguson-Smith M. A. (1984). Prenatal diagnosis of chromosome anomalies: who is at risk? In: Prenatal Diagnosis, Rodeck С. Н, Nicolaides К. Н. (eds.), John Wiley and Sons, Chichester, New York.

2293. Fletcher J. C., Berg К., Тrаnwy К. Е. (1985). Ethical aspects of medical genetics. A proposal for guidelines in genetic counseling, prenatal diagnosis and screening, Clin. Genet., 27, 199-205.

2294. Fraser F. С (1974). Genetic counseling, Am. J. Hum. Genet., 26, 636-659.

2295. Fraser F. C., Forse R. A. (1981). On genetic screening of donors for artificial insemination, Am. J. Med. Genet., 10, 399-405.

2296. French-Anderson W. (1984). Prospects for human gene therapy, Science, 226, 401-409.

2297. Fuhrmann W. (1971). Arteriosclerose; Erkrankungen der Koronargefasse. In: Humangenetik: Ein kurzes Handbuch in fiinf Banden, Vol. III/2, Becker P. E. (ed.), Thieme, Stuttgart, p. 508.

2298. Fuhrmann W., Weitzel H. K. (1985). Maternal serumalpha-fetoprotein screening for neural tube defects. Report of a combined study in Germany and short overview on screening populations with low birth prevalence of neural tube defects, Hum. Genet., 69, 47-61.

2299. Furrow B. R. (1984). Surrogate motherhood: A new option for parenting, Law, Medicine and Health Care, p. 106.

2300. Galen R. S., Gambino S. R. (1975). Beyond normality: The predictive value and efficiency of medical diagnoses, John Wiley and Sons, New York.

2301. Gitschier J., DraynaD., Tuddenham E. G. D., White R. L., Lawn R.M. (1985). Genetic mapping and diagnosis of haemophilia A achieved through a Bell polymorphism in the factor VIII gene, Nature, 314, 738-740.

2302. Graham J. B. (1977). Genetic counseling in classic hemophilia A, N. Engl. J. Med., 296, 996.

2303. Haldane J. B. S. (1963). Biological possibilities for the human species in the next ten thousand years. In: Man and his future, Wolstenholme G. (ed.), Churchill, London, pp. 337-361.

2304. Hammer R. E., Palmiter R. D., Brinster R. L. (1984). Partial correction of murine hereditary growth disorder by germlike incorporation of a new gene, Nature, 311, 65-67.

2305. Hammer R.E., Pursel V.G., Rexroad C. E.Jr., Wall R. J., Bolt D. J., EbertK.M., Palmiter R. D., Brinster R. L. (1985). Production of transgenic rabbits, sheep and pigs by microinjection, Nature, 315, 680-683.

2306. Harper P. S., O'Brien Т., Murray J. M. et al. (1983). The use of linked DNA polymorphisms for genotype prediction in families with Duchenne muscular dystrophy, J. Med. Genet., 20, 252-254.

2307. Harper P. S., Sarfarazi M. (1985). Genetic prediction and family structure in Huntington's disease, Br. Med. J., 290, 1929-1931.

2308. Harper P. S., Shaw D., Williams H (1984). Prenatal diagnosis and the muscular distrophies, In: Prenatal Diagnosis, Rodeck С. Н., Nicolaides К. Н. (eds.), John Wiley and Sons, Chichester, New York.

2309. Harris H. (1975). Prenatal diagnosis and selective abortion, Harvard University Press, Cambridge (MA).

2310. Hellerman J. G., Cone R. C., Potts J. Т., Rich A., Mulligan R. C., Kronenberg H. M. (1984). Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding prepropara-thyrpoid hormone, Proc. Natl. Acad. Sci. USA, 81, 5340-5344.

2311. Hess D. (1972). Transformationen an hoheren Organismen, Naturwissenschaften, 59, 348-355.

2312. Holzman N. A., Leonard С. О., Farfel M. R. (1981). Issues in antenatal and neonatal screening and surveillance for hereditary and congenital disorders, Ann. Rev. Public. Health., 2, 219-251.

2313. Holmes L. B. (1978). Genetic counseling for the older pregnant woman: new data and questions, N. Engl. J. Med., 298, 1419-1421.

2314. Horst J., Kluge F., Bayreuther K., Gerok W (1975). Gene transfer to human cells: Transducing phage X plac gene expression in GM! - gangliosidosis fibroblasts, Proc. Natl. Acad. Sci. USA, 72, 3531-3535.

2315. Horst J., Stanbro H, Merril C.R. (1980). On procaryotic gene expression in eucaryotic systems, Hum. Genet., 54, 289-302.

2316. Inman R. P. (1978). On the benefits and costs of genetic screeninG. Am. J. Hum. Genet., 30, 219-223.

2317. Nаkmа К., Hirose Т., Crea R., Riggs A. D., Heyneker H. L., Bolivar F., Boyer H. W (1977). Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin, Science, 198, 1056-1063.

2318. Jackson L. G. (1985). Firsttrimester diagnosis of fetal genetic disorders, Hosp. Pract., 20, 39-48.

2319. Jeanpierre M., Junien C. (1984). DNA analysis as clinical investigation: when and how, Ann. Genet., 27, 134-147.

2320. Kaback M. M., Zeiger R. S., Reynolds L. W, Sonneborn M. (1974). Approaches to the control and prevention of Tay-Sachs disease, ProG. Med. Genet., 10, 103-134.

2321. Kaback M. M. (ed.) (1977). Tay-Sachs disease: screening and prevention, Alan R. Liss, New York.

2322. Kazazian H. H. Jr., Boehm C. D., Dowling С. Е. (1985). Prenatal diagnosis of hemoglobinopathies by DNA analysis, Ann. N. Y. Acad. Sci., 445, 337-368.

2323. Kazy Z., Rozovsky I. S., BakharevV.A. (1982). Chorion biopsy in early pregnancy: a method for early prenatal diagnosis for inherited disorders, Pren. DiaG., 2, 39-45.

2323a. Kelly P. (1977). Dealing with Dilemma. A Manual for Genetic Couselors, Springer, New York.

2324. Kessler S. (1979). The genetic counselor as psychotherapist. In: Capron A. M., Lappe M., Murray R. F., Powledge Т. М., Twiss S. В., Bergsma D. (eds.), Genetic counselling: facts, values, and norms, Birth Defects, OriG. Art Ser. XV(2), Alan. R. Liss, New York.

2325. Kessler S. (1980). The psychological paradigm shift in genetic counseling, Soc. Biol., 27, 167-185.

2326. Kingston H. M., Sarfarazi M., Newcombe R. G., Willis N., Harper P. S. (1985). Carrier detection in Becker muscular dystrophy using creatine kinase estimation and DNA analysis, Clin. Genet., 27, 383-391.

2327. Klingmuller W (1976). Genmanipulation und Gentherapie, Springer, Berlin, Heidelberg, New York.

2328. Koch M., Fuhrmann W. (1985). Sibs of probands with neural tube defects-a study in the Federal Republic of Germany, Hum. Genet, 70, 74-79.

2329. Lawless E. W. (1977). Technology and social shock, Rutgers University Press, New Brunswick (N.J.).

2330. Lederberg J. (1963). Biological'future of man. In: Man and his future, Wolstenholme G. (ed.), Churchill, London, pp. 263-273.

2331. LeMeur M., Gerlinger P., Benoist C., Ma-this D. (1985). Correcting an immuneresponse deficiency by creating Ea gene transgenic mice, Nature, 316, 38-42.

2332. Leonard C., Chase G., Childs B. (1972). Genetic counseling: a consumer's view, N. Engl. J. Med., 287, 433.

2333. Levy H. L. (1974). Genetic screening, Adv. Hum. Genet., 4, 1.

2334. Lippman-Hand A., Fraser F. C. (1979). Genetic counselingthe postcounseling period: I. Parents' perceptions of incertainty, Am. J. Med. Genet., 4, 51-71.

2335. Lippman-Hand A., Fraser F. C. (1979). Genetic counseling - the postcounseling period: II. Making reproductive choices, Am. J. Med. Genet., 3, 73-87.

2336. MacSorley K. (1964). An investigation into the fertility rates of mentally ill patients, Ann. Hum. Genet., 27, 247.

2337. Marx J. L. (1985). Making maturant mice by gene transfer, Science, 228, 1516-1517.

2338. Matsunaga E. (1965). Measures affecting population trends and possible genetic consequences, United Nations World Populations Conference, Belgrad, August-September.

2339. McLaren A. (1973). Biological aspects of A. I. D. In: Law and ethics of A. I. D. and embryo transfer, Ciba Found Symp. (new series), 17, 3-9.

2340. McLaren A. (1985). Prenatal diagnosis before implantation: oportunities and problems, Pren. DiaG., 5, 85-90.

2341. Merill С. R., Geier M. R., Petricciani J. С. (1971). Bacterial virus gene expression in human cells, Nature, 233, 398-400.

2342. Mibashan R.S., Rodeck C. H. (1984). Haemophilia and other genetic defects of haemostasis. In: Prenatal Diagnosis, Rodeck С. Н., Nicolaides К. Н. (eds.), John Wiley and Sons, Chichester, New York.

2343. Miller A. D., Eckner R. J., Jolly J. D., Friedmann I., Verma I.M. (1984). Expression of a retrovirus encoding human HPRT in mice, Science, 223, 630-632.

2344. Milunsky A. (1975). The prevention of genetic disease and mental retardation, Saunders, Philadelphia.

2345. Modell B. (1984). Haemoglobinopathies-diagnosis by fetal blood samplinG. In: Prenatal Diagnosis, Rodeck С. Н., Nicolaides К. Н. (eds.), John Wiley and Sons, Chichester, New York.

2346. Modell B. (1985). Chorionic villus samplinG. Evaluation, safety and efficacy, Lancet, 1, 737-740.

2347. MotulskyA. G. (1973). Screening for sicklecell hemoglobinopathy and thalassemia, Isr. J. Med. Sci., 9, 1341-1349.

2348. Motulsky A. G. (1974). Brave new world? Current approaches to prevention, treatment, and research of genetic diseases raise ethical issues, Science, 185, 663 683.

2349. Motulsky A. G. (1975). Family detection of genetic disease. In: Early diagnosis and prevention of genetic disease, Went L., Vermeij-Keers C., van der Linden A. G. J. M. (eds.), University of Leiden Press, Leiden, pp. 101-110.

2350. Motulsky A. G. (1975). Problems of screening for genetic disease. In: Early diagnosis and prevention of genetic disease, Went L., Fermeij-Keers C., van der Linden A. G. J. M. (eds.), University of Leiden Press, Leiden, pp. 132-140.

2351. Motulsky A. G. (1979). Genetic counselinG. In: Textbook of medicine, 15th ed., Beeson P. В., McDermott W., Wyngaarden J. B. (eds.), Saunders, Philadelphia.

2352. Motulsky A. G. (1977). A genetical view of modern medicine. The Kober lecture, Transact Ass. Am. Phys., 40, 76-90.

2353. Motulsky A. G. (1982). Genetic counselinG. In: Cecil Textbook of Medicine, 16th ed., Wyngaarden J. В., Smith L. H. Jr. (eds.), Saunders, Philadelphia, pp. 23-26.

2354. Motulsky A. G. (1983). Impact of genetic manipulation on society and medicine, Science, 219, 135-140.

2355. Motulsky A. G. (1984). Genetic engineering, medicine and medical genetics, Biomedicine and Pharmacotherapy, 38, 185-186.

2356. Motulsky A. G., Fraser G. R. (1980). Effects of antenatal diagnosis and selective abortion on frequencies of genetic disorders, Clin. Obstet. Gynecol., 7, 121 134.

2357. Motulsky A. G., Murray J. (1983). Will prenatal diagnosis with selective abortion affect society's attitude toward the handicapped? In: Research Ethics, Berg K., Tranoy К. Е. (eds.), Alan. R. Liss, New York, pp. 277-291.

2358. Muller H. J. (1963). Genetic progress by voluntarily conducted germinal choice. In: Man and his future, Wolstenholme G. (ed.), Churchill, London, pp. 247-262.

2359. Nelson W. B., Swint J. M., Caskey С. Т. (1978). An economic evaluation of a genetic screening program for Tay-Sachs disease, Am. J. Hum. Genet, 30, 160-166.

2360. Nyhan W. L. (1985). Neonatal screening for inherited disease, N. Engl. J. Med., 313, 43-44.

2361. Old J. M., Weather all D. J., Wart R. H. T., Petrou M., Modell В., Rodeck С H, Warren R., Morsman J.M. (1985). First trimester diagnosis of the hemoglobin disorders, Ann. N. Y. Acad. Sci., 445, 349-356.

2362. Omenn G. S. (1982). Predictive identification of hypersusceptible individuals, J. Occup. Med., 24, 369-374.

2363. Orkin S. H. (1985). Molecular biology of P-thalassemia. In: First International symposium on the role of recombinant DNA in genetics, Teplitz R. L., Loukopoulos D. (eds.), Crete (in the press 1986).

2364. Ottman R., Pike M. C., King M.-C., Henderson B. E. (1983). Practical guide for estimating risk for familial breast cancer, Lancet, 2, 556-558.

2365. Palmiter R. D., Brinster R. L., Hammer R. E., Trumbauer M. E., Rosenfeld M. G., Birnberg N. C., Evans R. M. (1982). Dramatic growth of mice that develop from eggs micro-injected with metallothioneingrowth hormone fusion genes, Nature, 300, 611-615.

2366. Pauli R. M., Motulsky A. G. (1981). Risk counselling in autosomal dominant disorders with undetermined penetrance, J. Med. Genet., 18, 340-343.

2367. Penrose L. S. (1955). Parental age and mutation, Lancet, II, 3/2.

2368. Perry T. В., Fraser F. C. (1973). Variability of serum creatine phosphokinase activity in normal women and carriers of the gene for muscular dystrophy, Neurology, 23, 1316.

2369. Plachot M., Mandelbaum J. (1984). La fecondation in vitro, 5 ans, bientot l'age de raison, Ann. Genet, 27, 133.

2369a. Reeders S. T. et al. (1986). Two genetic markers closely linked to adult polycystic kidney disease on chromosome 16, Brit. Med. J., 292, 851-853.

2370. Reilly P. (1975). Genetic screening legislation, Adv. Hum. Genet, 5, 319-376.

2371. Richards B. W. (1967). Mongolism: The effect of trend in age at child birth and chromosomal type, J. Ment. Subnormality, 13, 3.

2372. Robertson F. W., dimming A. M. (1985). Effects of apoprotein E polymorphism on serum lipoprotein concentration, Arteriosclerosis, 5, 283-292.

2373. Robinson A. (1985). Prenatal diagnosis ' by amniocentesis, Ann. Rev. Med., 36, 13-16.

2374. Rodeck C. H. (1984). Obstetric techniques in prenatal diagnosis. In: Prenatal Diagnosis, Rodeck С. Н., Nicolaides К. Н. (eds.), John Wiley and Sons, Chichester, New York.

2375. Rorvik D. M. (1978). In his image: The cloning of a man, Lippincott, Philadelphia.

2376. Rosetelli C., Falchi A. M., Tuveri Т., Scalas M. Т., DiTucci A., Monni G., Cao A. (1985). Prenatal diagnosis of beta-thalassaemia with the synthetic-oligomer technique, Lancet, 1, 241-243.

2377. Scriver C. R. (1980). Predictive medicine: a goal for genetic screeninG. In: Neonatal Screening for Inborn Errors of Metabolism, Bickel H., Guthrie R., Hammersen G. (eds.), Springer, Berlin.

2378. Silvestroni E., Bianco I. (1975). Screening for microcytemia in Italy: analysis of data collected in the past 30 years, Am. J. Hum. Genet., 27, 198-212.

2379. Simoni G., Brambati В., Danesino C., Terzoli G. L., Romitti L., Rossella F., Fraccaro M. (1984). Diagnostic application of first trimester trophoblast sampling-100 pregnancies. Hum. Genet, 66, 252-259.

2379a. Simoni G., Gimelli G., Cuoco C., Romitti L., Terzoli G., Guerneri S., Rosella F., Pescetto L., Pezzolo A., Porta S., Brambati В., Porro E., Fraccaro M. (1986). First trimester fetal karyotyping: One thousand diagnoses, Hum. Genet, 72, 203-209.

2380. Sinsheimer R. L. (1977). Recombinant DNA, Ann. Rev. Biochem., 46, 415-438.

2381. Sinsheimer R. (1977). An evolutionary perspective for genetic engineering, New Scientist, 20, 150.

2382. Sorenson J. R., Swazey J. P., Scotch N. A., (eds.) (1981). Reproductive Pasts Reproductive Futures, Genetic Couselling and its Effectiveness, Birth Defects, OriG. Ser. XVII(4), Alan. R. Liss, New York.

2383. Szybalska E. H., Szybalski W. (1962). Genetics of human cell lines. IV. DNA-mediated heritable transformation of a biochemical trait, Proc. Natl. Acad. Sci. USA, 48, 2026-2034.

2384. Schrott H. G., Karp L., Omenn G. S. (1973). Prenatal prediction in myotonic dystrophy: guidelines for genetic counseling, Clin. Genet, 4, 38-45.

2385. Starlinger P. (1984). Medizinische Gentechnologie: Moglichkeiten und Grenzen, Deutsches Arzteblatt, 81, 2091-2098.

2386. Steptoe P. C., Edwards R. G. (1976). Reimplantation of a human embryo with subsequent tubal pregnancy, Lancet, I, 880-882.

2387. Steptoe P. C., Edwards R. G. (1978). Birth after the reimplantation of a human embryo, Lancet, II, 366.

2388. Terheggen H. G., Lowenthal A., Lavinha F., Colombo J. P., Rogers S. (1975). Unsuccessful trial of gene replasement in arginase deficiency, Z. Kinderheilkd., 119, 1-3.

2389. Trounson A., Mohr L. (1983). Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo, Nature, 305, 707-709.

2390. Ullrich A., Shine J., Chirgwin J., Pictet R., Tischer E., Rutter W.J., Goodman H.M. (1977). Rat insulin genes: Construction of plasmids containing the coding sequences, Science, 196, 1313-1319.

2391. Veal A. M. (1965). Intestinal polyposis. Eugenics laboratory memoirs XL, Cambridge University Press, London.

2392. Villa-Komaroff L., Efstratiadis A., Broome S., Lomedico P., Jlzzard R., Naber S. P., Chick W.L., Gilbert W. (1978). A bacterial clone synthesizing proinsulin, Proc. Natl. Acad. Sci. USA, 75, 3727-3731.

2393. Vogel F. (1957). Die eugenische Beratung beim Retinoblastom (Glioma retinae), Acta Genet., 7, 565-572.

2394. Vogel F. (1967). Wie stark ist die theoretische Haufigkeit von Trisomie-Syndromen durch Verschiebungen im Altersaufbau der Mutter zuruckgegangen? Zoologische Beitrage, 13, 451-462.

2395. Vogel F. (1973). Der Fortschritt als Gefahr und Chance fur die genetische Beschaffenheit des Menschen, Klin. Wochenschr., 51, 575-585.

2396. Vogel F. (1977). A probable sex difference in some mutation rates, Am. J. Hum. Genet., 29, 312-319.

2396a. Vogel F. (1985). New DNA techniqueschances and risks for mankind. First Int. Symp. on the Role of Recombinant DNA in Genetics, Crete (in the press, 1986).

2397. Vosberg H. P. (1977). Molecular cloning of DNA. An introduction into techniques and problems, Hum. Genet, 40, 1-72.

2398. Wald N. J., Cuckle H. S. (1984). Open neural tube defects. In: Antenatal and Neunatal Screening, Wald N. J. (ed.), London, Oxford.

2399. Ward R. H. T. (1984). First trimester chorionic villus samplinG. In: Prenatal diagnosis, Rodeck С. Н., Nicolaides К. Н. (eds.), John Wiley and Sons, Chichester, New York.

2400. Weather all D. (1984). Gene transfection. A new step nearer gene therapy? Nature, 310, 451-452.

2401. Wendt G. G., Landzettel H. J., Unterreiner I. (1959). Das Erkrankugsalter bei der Huntingtonschen Chorea, Acta Genet. (Basel), 9, 18.

2402. Williams D. A., Lemischka I. R., Nathan D. G., Mulligan R. C. (1984). Introduction of new genetic material into pluripotent haemotapretic stem cells of the mouse, Nature, 310, 476-480. 2403. Wood L., Trounson A. (1984). Clinical in vitro fertilization, Springer, Berlin, Heidelberg, New York.